CONTENTS:- Bioinformatics: Introduction, databases and tools; Key terms in bioinformatics; Comparative analysis of bioinformatics tools; Application of reusability in bioinformtics tools; Drug discovery; Drug designing; Rational approach to drug designing; Molecular docking in drug desigining; Structural analysis of the p53 tumour-suppressor protein and their gener sequencing regulations; SiRAN and RNAi; Rhizoctonia: A database approach-I; Rhizoctonia: A database approach-II; Study of putative homeodomain proteins in a few pathogenic species of eubacteriae; Drug discovery and design.