CONTENTS:- 1. Transgenic farm animals; 2. Development of genetic tools for transgenic animals; 3. One gene is not enough: transgene detection, expression and control; 4. Embryonic stem cells in agricultural species; 5. Nuclear transfer in the production of transgenic farm animals; 6. Embryonic stem cell chimeras and somatic cell nuclear transplantation for production of transgenic cattle; 7. Status of sperm-mediated delivery methods for gene transfer; 8. Understanding the origin of Avian primordial germ cells: implications for germ cell culture and transgenesis in poultry; 9. Generation of transgenic poultry by transfection of primordial germ cells; 10. Expression of insulin-like growth factor-I in skeletal muscle of transgenic swine; 11. Production and analysis of transgenic pigs containing a metallothionein porcine growth hormone gene construct; 12. The utilization of bacterial genes to modify domestic animal biochemistry; 13. Production of transgenic cattle expressing a recombinant protein in milk; 14. Changing the composition and properties of milk; 15. Comparison of traditional breeding and transgenesis in farmed fish with implications for growth enhancement and fitness; 16. Direct and correlated responses to short-term selection of 8-week body weight in lines of transgenic (oMt1a-oGH) mice; 17. Ethics, animal welfare and transgenic farm animals; 18. The future of transgenic farm animals.
DESCRIPTION
In the past decade, a number of advances have been made in genetic engineering as applied to farmed animals. Current knowledge, methodology, technical improvements and successes in applications of transgenic technology to a range of animal which are important in agriculture are brought together for the first time under one roof. The book is essential reading for research workers in animal genetics, breeding and biotechnology.
